TNNT2

Across TCGA cell cohorts, TNNT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,931 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNNT2-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Response to indole-3-methanol, and Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with TNNT2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TNNT2-to-partner and partner-to-TNNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by TNNT2-low versus TNNT2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNT2→partner) and Y-score (partner→TNNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of mRNA metabolic process →	+0.063	+1.387	<.001	.002	3	10
STOMACH	Response to indole-3-methanol →	+0.206	+1.947	<.001	<.001	3	9
STOMACH	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.110	+1.595	<.001	.007	3	9
SOFT_TISSUE	mRNA stabilization →	+0.074	+3.130	<.001	.001	3	9
SOFT_TISSUE	RNA catabolic process →	+0.035	+2.971	.007	.002	3	8
STOMACH	Cellular response to indole-3-methanol →	+0.186	+1.739	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,931 associations by consensus.

Negative regulation of mRNA metabolic process by TNNT2 expression — OVARY

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