TNNT1

Across TCGA cell cohorts, TNNT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,161 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNNT1-associated GO terms across cancer lineages are Negative regulation of muscle contraction, Multicellular organismal movement, and Positive regulation of stem cell proliferation. Each is linked with TNNT1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TNNT1-to-partner and partner-to-TNNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of muscle contraction grouped by TNNT1-low versus TNNT1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNT1→partner) and Y-score (partner→TNNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of muscle contraction →	+0.218	+4.049	<.001	<.001	3	13
SOFT_TISSUE	Multicellular organismal movement →	+0.202	+2.792	<.001	<.001	3	10
SKIN	Positive regulation of stem cell proliferation →	+0.126	+1.238	<.001	.003	3	9
SOFT_TISSUE	Skeletal muscle contraction →	+0.206	+2.271	<.001	.001	2	10
SOFT_TISSUE	Musculoskeletal movement →	+0.204	+3.084	<.001	<.001	3	9
SKIN	Myofibril assembly →	+0.167	+1.954	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,161 associations by consensus.

Negative regulation of muscle contraction by TNNT1 expression — SOFT_TISSUE

Explore this box plot interactively →