TNNI3K

Across TCGA patient cohorts, TNNI3K protein abundance is significantly associated with the RNA expression of many other genes, with 15,493 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNNI3K-associated genes across cancer lineages are DDX55, KIF14, and HELLS. Each is linked with TNNI3K in more than 6 cancer types. Because this analysis shows association rather than direction, both TNNI3K-to-partner and partner-to-TNNI3K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNI3K versus DDX55 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI3K→partner) and Y-score (partner→TNNI3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DDX55 →	+0.577	+0.345	.001	.003	3	6
GBM	KIF14 →	+0.991	+0.609	<.001	<.001	3	6
GBM	HELLS →	+0.841	+0.606	<.001	<.001	3	6
HNSC	TOP2A →	+1.126	+0.391	.001	<.001	3	6
HNSC	KIF11 →	+0.872	+0.368	.003	.002	3	6
COAD	SKA1 →	+0.893	+0.673	.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,493 associations by consensus.

TNNI3K vs DDX55 — HNSC

Explore this scatter interactively →