TNNI3

Across TCGA cell cohorts, TNNI3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,240 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNNI3-associated GO terms across cancer lineages are Actin-myosin filament sliding, Aerobic electron transport chain, and Cytoplasmic translation. Each is linked with TNNI3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TNNI3-to-partner and partner-to-TNNI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin-myosin filament sliding grouped by TNNI3-low versus TNNI3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI3→partner) and Y-score (partner→TNNI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Actin-myosin filament sliding →	-0.332	-1.821	<.001	<.001	3	9
BONE	Aerobic electron transport chain →	+0.094	+2.789	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.084	+1.180	.002	.002	3	8
BONE	Oxidative phosphorylation →	+0.099	+3.180	<.001	<.001	3	8
LIVER	Nervous system process involved in regulation of systemic arterial blood pressure →	-0.356	-1.446	.003	.005	2	9
OESOPHAGUS	Regulation of myoblast fusion →	+0.111	+1.912	.007	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

Actin-myosin filament sliding by TNNI3 expression — SOFT_TISSUE

Explore this box plot interactively →