TNNC1

Across TCGA patient cohorts, TNNC1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,973 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TNNC1-associated genes across cancer lineages are LILRB5, ADRA2A, and SORCS2. Each is linked with TNNC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNC1-to-partner and partner-to-TNNC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNC1 versus LILRB5 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNC1→partner) and Y-score (partner→TNNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LILRB5 →	+0.706	+1.359	<.001	<.001	3	2
OV	ADRA2A →	+1.046	+0.827	<.001	.003	3	2
HNSC	SORCS2 →	+1.077	+1.423	<.001	<.001	3	2
OV	HBA2 →	+1.305	+0.870	.001	.005	3	2
HNSC	LINC01362 →	-0.950	-1.125	.005	.003	3	2
HNSC	LINC02315 →	-1.329	-1.194	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,973 associations by consensus.

TNNC1 vs LILRB5 — HNSC

Explore this scatter interactively →