TNNC1

Across TCGA cell cohorts, TNNC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,169 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNNC1-associated GO terms across cancer lineages are Regulation of muscle filament sliding, Positive regulation of establishment of T cell polarity, and Negative regulation of mRNA catabolic process. Each is linked with TNNC1 in more than 17 cancer types. Because this analysis shows association rather than direction, both TNNC1-to-partner and partner-to-TNNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of muscle filament sliding grouped by TNNC1-low versus TNNC1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNC1→partner) and Y-score (partner→TNNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of muscle filament sliding →	+2.084	+3.580	<.001	<.001	3	18
BREAST	Positive regulation of establishment of T cell polarity →	-0.186	-1.373	.002	.003	2	10
BREAST	Negative regulation of mRNA catabolic process →	+0.063	+1.580	<.001	<.001	3	9
URINARY_TRACT	Branched-chain amino acid catabolic process →	+0.087	+2.644	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Regulation of actin filament-based movement →	+0.161	+2.612	<.001	<.001	3	8
KIDNEY	Actin-myosin filament sliding →	-0.172	-0.636	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,169 associations by consensus.

Regulation of muscle filament sliding by TNNC1 expression — PANCREAS

Explore this box plot interactively →