TNN

Across TCGA patient cohorts, TNN protein abundance is significantly associated with the RNA expression of many other genes, with 9,504 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TNN-associated genes across cancer lineages are POSTN, COL1A2, and TIMP3. Each is linked with TNN in more than 5 cancer types. Because this analysis shows association rather than direction, both TNN-to-partner and partner-to-TNN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNN versus POSTN in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNN→partner) and Y-score (partner→TNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	POSTN →	+3.966	+1.668	<.001	<.001	3	6
OV	COL1A2 →	+1.577	+0.963	.009	.001	3	6
OV	TIMP3 →	+3.461	+1.474	<.001	<.001	3	5
OV	TNFSF4 →	+1.673	+1.616	<.001	<.001	3	5
BRCA	GLT8D2 →	+1.020	+0.893	<.001	<.001	3	5
OV	CALD1 →	+1.355	+1.074	.004	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,504 associations by consensus.

TNN vs POSTN — OV

Explore this scatter interactively →