TNKS2-AS1

Across TCGA patient cohorts, TNKS2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,985 significant associations in total. THCA shows the largest number of these associations.

The most reproducible TNKS2-AS1-associated GO terms across cancer lineages are Macromolecule methylation, Mitochondrial respiratory chain complex assembly, and Respiratory chain complex III assembly. Each is linked with TNKS2-AS1 in more than 18 cancer types. Because this analysis shows association rather than direction, both TNKS2-AS1-to-partner and partner-to-TNKS2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by TNKS2-AS1-low versus TNKS2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNKS2-AS1→partner) and Y-score (partner→TNKS2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Macromolecule methylation →	+0.035	+0.297	.001	<.001	3	19
ESCA	Mitochondrial respiratory chain complex assembly →	+0.040	+0.238	.002	.003	1	19
ESCA	Respiratory chain complex III assembly →	+0.039	+0.236	<.001	.003	3	16
ESCA	Peptidyl-lysine modification →	+0.059	+0.432	.005	<.001	2	17
STAD	Methylation →	+0.033	+0.192	.001	.001	2	17
ESCA	Regulation of protein localization to cilium →	+0.058	+0.380	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,985 associations by consensus.

Macromolecule methylation by TNKS2-AS1 expression — ESCA

Explore this box plot interactively →