TNKS2-AS1

Across TCGA pan-cancer cohorts, TNKS2-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated TNKS2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TNKS2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TNKS2-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and CESC show a favorable association.

ACC, KIRC, and ESCA are the cancer types where TNKS2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.376	0.830	<.001	109	view →
KIRC	DFS	Quartile	II,III,IV	0.678	0.857	.003	56	view →
ESCA	DFS	Tertile	All	0.451	0.206	<.001	52	view →
CESC	OS	Median	All	0.919	0.827	.002	36	view →
UVM	DFS	Quartile	All	0.410	0.838	.005	28	view →
UCS	OS	Median	All	0.681	0.453	.019	24	view →
UCEC	DFS	Quartile	All	0.609	0.801	.009	24	view →
LUAD	DFS	Median	IV	0.817	0.386	.003	22	view →
OV	DFS	Median	III,IV	0.581	0.482	.006	20	view →
LGG	OS	Quartile	All	0.932	0.810	<.001	16	view →
READ	OS	Tertile	IV	0.649	1.000	.024	16	view →
BLCA	OS	Quartile	All	0.579	0.837	.003	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

TNKS2-AS1–ACC (OS)

Open the ACC breakdown →