TNIP3

Across TCGA patient cohorts, TNIP3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,949 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNIP3-associated genes across cancer lineages are CXCL8, FAM30A, and YWHAE. Each is linked with TNIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNIP3-to-partner and partner-to-TNIP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNIP3 versus CXCL8 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNIP3→partner) and Y-score (partner→TNIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CXCL8 →	+2.566	+0.876	<.001	<.001	3	2
LUAD	FAM30A →	-1.300	-0.644	.001	.007	3	2
UCEC	YWHAE →	+0.805	+2.632	.007	.003	3	1
UCEC	AKAP12 →	+2.275	+2.213	<.001	<.001	3	1
UCEC	ASCC1 →	+0.577	+2.061	.001	.003	3	1
UCEC	ZGRF1 →	+1.182	+2.387	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,949 associations by consensus.

TNIP3 vs CXCL8 — LSCC

Explore this scatter interactively →