TNIP2

Across TCGA cell cohorts, TNIP2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TNIP2-associated genes across cancer lineages are SMIM9, TAS2R39, and OR2C1. Each is linked with TNIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNIP2-to-partner and partner-to-TNIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM9 grouped by TNIP2-low versus TNIP2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNIP2→partner) and Y-score (partner→TNIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SMIM9 →	+0.032	+5.754	<.001	.002	3	1
CNS	TAS2R39 →	+0.044	+4.981	<.001	.008	3	1
LARGE_INTESTINE	OR2C1 →	+0.126	+3.725	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SMIM9 by TNIP2 expression — CNS

Explore this box plot interactively →