TNIP1

Across TCGA pan-cancer cohorts, TNIP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TNIP1 data layer compared with 24 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TNIP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TNIP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, LSCC, and HNSC are the cancer types where TNIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.975	0.741	.010	54	view →
LSCC	OS	Quartile	II,III,IV	0.594	1.000	.001	38	view →
HNSC	OS	Median	IV	0.965	0.713	.003	33	view →
CCRCC	DFS	Median	IV	0.781	0.220	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TNIP1–UCEC (DFS)

Open the UCEC breakdown →