TNFSF8

Across TCGA patient cohorts, TNFSF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,068 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFSF8-associated proteins across cancer lineages are RCSD1, SASH3, and ADA2. Each is linked with TNFSF8 in more than 9 cancer types. Because this analysis shows association rather than direction, both TNFSF8-to-partner and partner-to-TNFSF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF8 versus RCSD1 in GBM, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF8→partner) and Y-score (partner→TNFSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCSD1 →	+0.675	+1.043	<.001	<.001	3	10
GBM	SASH3 →	+0.594	+1.069	<.001	<.001	3	10
LSCC	ADA2 →	+0.608	+0.879	<.001	<.001	3	10
GBM	DOCK2 →	+0.827	+1.099	<.001	<.001	3	10
GBM	FYB1 →	+0.876	+0.992	<.001	<.001	3	10
GBM	ABI3 →	+0.656	+0.948	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,068 associations by consensus.

TNFSF8 vs RCSD1 — GBM

Explore this scatter interactively →