TNFSF8

Across TCGA patient cohorts, TNFSF8 protein abundance is significantly associated with the RNA expression of many other genes, with 321 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFSF8-associated genes across cancer lineages are CNDP1, IGF2, and SNORA41B. Each is linked with TNFSF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF8-to-partner and partner-to-TNFSF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF8 versus CNDP1 in LUAD, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF8→partner) and Y-score (partner→TNFSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CNDP1 →	+0.105	+1.390	.002	.007	3	1
LUAD	IGF2 →	+0.183	+0.929	.008	.006	3	1
LUAD	SNORA41B →	+2.009	+1.314	<.001	.002	3	1
LUAD	RPL32P6 →	+1.115	+1.390	<.001	.007	3	1
LUAD	SPTLC1P5 →	+1.154	+1.314	<.001	.002	3	1
LUAD	RPL21P43 →	+0.746	+0.930	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 321 associations by consensus.

TNFSF8 vs CNDP1 — LUAD

Explore this scatter interactively →