TNFSF8

Across TCGA cell cohorts, TNFSF8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,743 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNFSF8-associated GO terms across cancer lineages are Endodermal cell fate commitment, Very-low-density lipoprotein particle clearance, and Actin filament capping. Each is linked with TNFSF8 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFSF8-to-partner and partner-to-TNFSF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endodermal cell fate commitment grouped by TNFSF8-low versus TNFSF8-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF8→partner) and Y-score (partner→TNFSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Endodermal cell fate commitment →	+0.161	+0.048	<.001	.004	3	3
STOMACH	Very-low-density lipoprotein particle clearance →	-0.851	-0.152	.005	.005	3	3
STOMACH	Actin filament capping →	+0.130	+0.134	.002	.003	3	3
URINARY_TRACT	MyD88-dependent toll-like receptor signaling pathway →	+0.063	+0.062	.004	.007	3	3
OVARY	Regulation of vesicle docking →	+0.094	+0.029	.004	.002	3	3
BLOOD_Leukemia	Embryonic skeletal limb joint morphogenesis →	+0.109	+0.787	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,743 associations by consensus.

Endodermal cell fate commitment by TNFSF8 expression — OVARY

Explore this box plot interactively →