TNFSF8

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TNFSF8 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TNFSF8-associated genes across cancer lineages are OR56A1. Each is linked with TNFSF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF8-to-partner and partner-to-TNFSF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A1 grouped by TNFSF8-low versus TNFSF8-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF8→partner) and Y-score (partner→TNFSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINOR56A1 →+0.012+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR56A1 by TNFSF8 expression — SKIN

Box plot of OR56A1 in TNFSF8-low vs TNFSF8-high samples in SKIN.

Explore this box plot interactively →

Exploration