TNFSF13B

Across TCGA pan-cancer cohorts, TNFSF13B Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TNFSF13B data layer compared with 25 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TNFSF13B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TNFSF13B expression acts as an unfavorable survival marker.

COAD, BRCA, and SCLC are the cancer types where TNFSF13B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.159	0.799	.002	18	view →
BRCA	OS	Median	All	0.107	0.578	<.001	12	view →
SCLC	OS	Median	All	0.082	0.708	<.001	12	view →
BLCA	DFS	Median	III,IV	0.184	0.574	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TNFSF13B–COAD (OS)

Open the COAD breakdown →