TNFSF13B

Across TCGA patient cohorts, TNFSF13B mutation is significantly associated with the RNA expression of many other genes, with 876 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF13B-associated genes across cancer lineages are RN7SKP245, BOD1P1, and H4C7. Each is linked with TNFSF13B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF13B-to-partner and partner-to-TNFSF13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP245 grouped by TNFSF13B-low versus TNFSF13B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF13B→partner) and Y-score (partner→TNFSF13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP245 →	+0.130	+5.812	<.001	.003	3	2
SKCM	BOD1P1 →	+0.138	+5.402	<.001	.001	3	2
UCEC	H4C7 →	+0.194	+1.961	<.001	.009	3	2
CESC	RNA5SP75 →	+0.309	+5.103	.007	.008	3	1
CESC	TLE7 →	+0.050	+5.010	.008	.009	3	1
CESC	ATP5MGP7 →	+0.220	+5.812	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 876 associations by consensus.

RN7SKP245 by TNFSF13B expression — CESC

Explore this box plot interactively →