TNFSF13B

Across TCGA patient cohorts, TNFSF13B mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF13B-associated genes across cancer lineages are 14-3-3_beta, MEK1, and p62 Lck ligand. Each is linked with TNFSF13B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF13B-to-partner and partner-to-TNFSF13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by TNFSF13B-low versus TNFSF13B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF13B→partner) and Y-score (partner→TNFSF13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.096	-2.973	.040	.035	3	1
UCEC	MEK1 →	+0.348	+2.584	.041	.011	3	1
UCEC	p62 Lck ligand →	+0.371	+2.817	.014	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

14-3-3_beta by TNFSF13B expression — UCEC

Explore this box plot interactively →