TNFSF13B

Across TCGA cell cohorts, TNFSF13B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,241 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFSF13B-associated GO terms across cancer lineages are Cotranslational protein targeting to membrane, Cytoplasmic pattern recognition receptor signaling pathway, and Positive regulation of innate immune response. Each is linked with TNFSF13B in more than 9 cancer types. Because this analysis shows association rather than direction, both TNFSF13B-to-partner and partner-to-TNFSF13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cotranslational protein targeting to membrane grouped by TNFSF13B-low versus TNFSF13B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF13B→partner) and Y-score (partner→TNFSF13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cotranslational protein targeting to membrane →	+0.093	+2.593	<.001	<.001	3	10
PANCREAS	Cytoplasmic pattern recognition receptor signaling pathway →	+0.068	+0.532	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of innate immune response →	+0.051	+0.446	.003	.003	3	9
PANCREAS	Negative regulation of response to biotic stimulus →	+0.093	+0.726	.001	<.001	3	9
PANCREAS	Antigen processing and presentation of peptide antigen via MHC class I →	+0.134	+0.497	<.001	<.001	3	8
SOFT_TISSUE	Negative regulation of T cell cytokine production →	+0.848	+0.448	<.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,241 associations by consensus.

Cotranslational protein targeting to membrane by TNFSF13B expression — BLOOD_Leukemia

Explore this box plot interactively →