TNFSF10

Across TCGA patient cohorts, TNFSF10 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,202 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFSF10-associated proteins across cancer lineages are DDX60, DTX3L, and IFIT3. Each is linked with TNFSF10 in more than 8 cancer types. Because this analysis shows association rather than direction, both TNFSF10-to-partner and partner-to-TNFSF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF10 versus DDX60 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF10→partner) and Y-score (partner→TNFSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDX60 →	+0.696	+1.986	<.001	<.001	3	9
OV	DTX3L →	+0.578	+1.630	<.001	<.001	3	8
HNSC	IFIT3 →	+1.441	+0.955	<.001	<.001	3	8
OV	UBE2L6 →	+0.518	+1.308	<.001	<.001	3	8
OV	XAF1 →	+0.812	+1.606	<.001	.001	3	7
OV	DTX3L_S539 →	+0.690	+1.050	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,202 associations by consensus.

TNFSF10 vs DDX60 — OV

Explore this scatter interactively →