TNFSF10

Across TCGA patient cohorts, TNFSF10 protein abundance is significantly associated with the RNA expression of many other genes, with 5,707 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TNFSF10-associated genes across cancer lineages are IFI44L, UBE2L6, and PLSCR1. Each is linked with TNFSF10 in more than 5 cancer types. Because this analysis shows association rather than direction, both TNFSF10-to-partner and partner-to-TNFSF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF10 versus IFI44L in PDAC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF10→partner) and Y-score (partner→TNFSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	IFI44L →	+1.500	+0.853	<.001	<.001	3	6
HNSC	UBE2L6 →	+0.976	+0.431	.006	<.001	3	6
OV	PLSCR1 →	+1.043	+0.693	.005	.009	2	6
HNSC	OAS2 →	+1.146	+0.505	.001	.002	3	5
HNSC	IFIT3 →	+1.794	+0.711	<.001	<.001	3	5
BRCA	NMI →	+0.635	+0.528	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

TNFSF10 vs IFI44L — PDAC

Explore this scatter interactively →