TNFSF10

Across TCGA patient cohorts, TNFSF10 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TNFSF10-associated genes across cancer lineages are c-Kit. Each is linked with TNFSF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF10-to-partner and partner-to-TNFSF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, c-Kit grouped by TNFSF10-low versus TNFSF10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF10→partner) and Y-score (partner→TNFSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	c-Kit →	-0.648	-3.169	.038	.017	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

c-Kit by TNFSF10 expression — SKCM

Explore this box plot interactively →