TNFRSF8

Across TCGA patient cohorts, TNFRSF8 RNA expression is significantly associated with the RNA expression of many other genes, with 15,524 significant associations in total. UVM shows the largest number of these associations.

The most reproducible TNFRSF8-associated genes across cancer lineages are GNGT2, NFKB2, and SNX20. Each is linked with TNFRSF8 in more than 29 cancer types. Because this analysis shows association rather than direction, both TNFRSF8-to-partner and partner-to-TNFRSF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF8 versus GNGT2 in SKCM, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF8→partner) and Y-score (partner→TNFRSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GNGT2 →	+1.269	+0.943	<.001	<.001	3	30
TGCT	NFKB2 →	+1.297	+2.210	<.001	<.001	3	30
SCLC	SNX20 →	+2.046	+0.648	<.001	<.001	3	29
BLCA	GPR34 →	+1.387	+0.711	<.001	<.001	3	29
LAML	CCR2 →	+1.947	+1.066	<.001	<.001	3	29
SCLC	THEMIS2 →	+2.218	+0.541	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,524 associations by consensus.

TNFRSF8 vs GNGT2 — SKCM

Explore this scatter interactively →