Across TCGA patient cohorts, TNFRSF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,917 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFRSF4-associated proteins across cancer lineages are WAS, LCP1, and LSP1. Each is linked with TNFRSF4 in more than 8 cancer types. Because this analysis shows association rather than direction, both TNFRSF4-to-partner and partner-to-TNFRSF4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF4→partner) and Y-score (partner→TNFRSF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WAS →	+0.427	+0.640	<.001	<.001	3	9
GBM	LCP1 →	+0.640	+0.451	<.001	.002	3	9
UCEC	LSP1 →	+0.681	+1.139	<.001	<.001	3	9
OV	PTPN7 →	+0.513	+0.597	.001	.006	3	8
UCEC	DOCK8 →	+0.464	+0.705	.001	.005	3	8
GBM	DOK2 →	+0.574	+0.673	.005	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,917 associations by consensus.

Exploration

TNFRSF4 survival (RNA) · tumor vs normal (RNA) · all TNFRSF4 data types