TNFRSF21

Across TCGA patient cohorts, TNFRSF21 protein abundance is significantly associated with the RNA expression of many other genes, with 6,231 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TNFRSF21-associated genes across cancer lineages are MDFI, PLAUR, and FHOD3. Each is linked with TNFRSF21 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFRSF21-to-partner and partner-to-TNFRSF21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF21 versus MDFI in LUAD, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF21→partner) and Y-score (partner→TNFRSF21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MDFI →	+1.090	+0.952	<.001	<.001	3	3
LUAD	PLAUR →	+0.909	+0.753	.001	<.001	3	3
LSCC	FHOD3 →	+1.155	+0.611	<.001	<.001	3	3
UCEC	N4BP2L1 →	-0.703	-0.626	.009	.004	3	3
PDAC	SLC16A3 →	+0.926	+0.708	<.001	<.001	3	3
LSCC	LRTM1 →	-0.755	-0.710	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,231 associations by consensus.

TNFRSF21 vs MDFI — LUAD

Explore this scatter interactively →