TNFRSF1A

Across TCGA patient cohorts, TNFRSF1A protein abundance is significantly associated with the RNA expression of many other genes, with 6,657 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TNFRSF1A-associated genes across cancer lineages are GAPDH, GALNT2, and P4HB. Each is linked with TNFRSF1A in more than 3 cancer types. Because this analysis shows association rather than direction, both TNFRSF1A-to-partner and partner-to-TNFRSF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF1A versus GAPDH in LUAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF1A→partner) and Y-score (partner→TNFRSF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GAPDH →	+0.904	+0.509	<.001	<.001	3	4
HNSC	GALNT2 →	+0.619	+0.488	<.001	.002	3	4
CCRCC	P4HB →	+0.464	+0.271	.003	.008	3	4
HNSC	SMIM3 →	+1.369	+0.557	.001	.004	3	4
LSCC	YPEL1 →	-0.801	-0.385	<.001	<.001	3	3
HNSC	MTMR8 →	-0.790	-0.650	.005	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,657 associations by consensus.

TNFRSF1A vs GAPDH — LUAD

Explore this scatter interactively →