TNFRSF1A

Across TCGA cell cohorts, TNFRSF1A protein abundance is significantly associated with the RNA expression of many other genes, with 1,558 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNFRSF1A-associated genes across cancer lineages are RAB2A, GALNT10, and ESCO2. Each is linked with TNFRSF1A in more than 4 cancer types. Because this analysis shows association rather than direction, both TNFRSF1A-to-partner and partner-to-TNFRSF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF1A versus RAB2A in SKIN, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF1A→partner) and Y-score (partner→TNFRSF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RAB2A →	-0.707	-1.225	.004	<.001	3	5
SKIN	GALNT10 →	-0.715	-1.481	.006	.009	3	5
LUNG_NSCLC_LUSC	ESCO2 →	+1.155	+1.018	.001	.005	3	4
BONE	CACNB2 →	+1.896	+1.568	.001	.004	3	4
OESOPHAGUS	BRCC3 →	+1.159	+1.146	.001	.002	3	4
OVARY	SCLY →	+0.965	+0.844	.009	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,558 associations by consensus.

TNFRSF1A vs RAB2A — SKIN

Explore this scatter interactively →