TNFRSF19

Across TCGA cell cohorts, TNFRSF19 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFRSF19-associated genes across cancer lineages are LYZL6, TBX22, and COX6A2. Each is linked with TNFRSF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF19-to-partner and partner-to-TNFRSF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYZL6 grouped by TNFRSF19-low versus TNFRSF19-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF19→partner) and Y-score (partner→TNFRSF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LYZL6 →	+0.149	+4.544	<.001	.003	3	1
LARGE_INTESTINE	TBX22 →	+0.030	+3.632	<.001	.003	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	ENPP6 →	+0.037	+4.115	.001	.001	3	1
LARGE_INTESTINE	CFAP47 →	+0.196	+3.453	.008	.009	3	1
LARGE_INTESTINE	TFDP3 →	+0.018	+3.196	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

LYZL6 by TNFRSF19 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →