Across TCGA patient cohorts, TNFRSF18 mutation is significantly associated with the RNA expression of many other genes, with 128 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TNFRSF18-associated genes across cancer lineages are RN7SL794P, NXPE2P1, and SNORD116-10. Each is linked with TNFRSF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF18-to-partner and partner-to-TNFRSF18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF18→partner) and Y-score (partner→TNFRSF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL794P →	+0.172	+3.631	<.001	.002	3	2
COAD	NXPE2P1 →	+0.574	+4.181	<.001	.009	3	2
UCEC	SNORD116-10 →	+0.518	+5.335	<.001	.003	3	2
UCEC	RNA5SP205 →	+0.294	+4.852	.009	.006	3	2
SKCM	OR51C1P →	+0.035	+4.913	<.001	<.001	3	2
SKCM	RN7SKP273 →	+0.158	+2.992	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 128 associations by consensus.

Exploration

TNFRSF18 survival (RNA) · tumor vs normal (RNA) · all TNFRSF18 data types