TNFRSF14-AS1

Across TCGA pan-cancer cohorts, TNFRSF14-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TNFRSF14-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TNFRSF14-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TNFRSF14-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

BLCA, BRCA, and HNSC are the cancer types where TNFRSF14-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.694	0.524	<.001	127	view →
BRCA	OS	Median	All	0.951	0.898	<.001	84	view →
HNSC	DFS	Quartile	All	0.782	0.640	.001	83	view →
COAD	OS	Quartile	IV	0.508	0.934	.002	50	view →
UCEC	OS	Tertile	All	0.929	0.853	.009	48	view →
LGG	DFS	Median	All	0.281	0.466	<.001	40	view →
SKCM	DFS	Median	III,IV	0.615	0.366	<.001	38	view →
KIRP	OS	Tertile	II,III,IV	0.836	0.517	.009	23	view →
UVM	OS	Quartile	III,IV	0.386	1.000	.005	20	view →
ACC	OS	Median	IV	0.842	0.244	.001	18	view →
MESO	DFS	Quartile	All	0.500	0.259	.003	15	view →
SARC	OS	Tertile	All	0.875	0.640	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TNFRSF14-AS1–BLCA (OS)

Open the BLCA breakdown →