TNFRSF13C

Across TCGA patient cohorts, TNFRSF13C mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible TNFRSF13C-associated genes across cancer lineages are RNU6-365P, RNU4ATAC5P, and MTND2P7. Each is linked with TNFRSF13C in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF13C-to-partner and partner-to-TNFRSF13C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-365P grouped by TNFRSF13C-low versus TNFRSF13C-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF13C→partner) and Y-score (partner→TNFRSF13C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-365P →	+0.270	+7.930	<.001	.008	3	1
LUAD	RNU4ATAC5P →	+0.279	+7.930	<.001	.008	3	1
LUAD	MTND2P7 →	+0.053	+7.930	.009	.008	3	1
LUAD	MIR4695 →	+0.423	+7.930	<.001	.008	3	1
BLCA	IGKV3-25 →	+0.203	+5.177	.001	.007	3	1
BLCA	RNU6-799P →	+0.410	+4.973	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

RNU6-365P by TNFRSF13C expression — LUAD

Explore this box plot interactively →