TNFRSF13C

Across TCGA cell cohorts, TNFRSF13C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,599 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFRSF13C-associated GO terms across cancer lineages are Regulation of DNA repair, Telomere maintenance, and Regulation of double-strand break repair. Each is linked with TNFRSF13C in more than 15 cancer types. Because this analysis shows association rather than direction, both TNFRSF13C-to-partner and partner-to-TNFRSF13C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by TNFRSF13C-low versus TNFRSF13C-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF13C→partner) and Y-score (partner→TNFRSF13C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of DNA repair →	+0.072	+0.582	<.001	<.001	3	16
BONE	Telomere maintenance →	+0.089	+1.170	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.075	+0.530	<.001	<.001	3	13
BLOOD_Lymphoma	Regulation of ATPase-coupled calcium transmembrane transporter activity →	-0.244	-2.318	<.001	<.001	3	13
BONE	Regulation of DNA recombination →	+0.076	+0.830	<.001	<.001	3	13
STOMACH	Positive regulation of double-strand break repair →	+0.090	+0.801	.002	.003	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,599 associations by consensus.

Regulation of DNA repair by TNFRSF13C expression — SOFT_TISSUE

Explore this box plot interactively →