TNFRSF12A

Across TCGA patient cohorts, TNFRSF12A RNA expression is significantly associated with the protein abundance of many other proteins, with 19,128 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFRSF12A-associated proteins across cancer lineages are ZYX, PLAU, and CCN1. Each is linked with TNFRSF12A in more than 7 cancer types. Because this analysis shows association rather than direction, both TNFRSF12A-to-partner and partner-to-TNFRSF12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF12A versus ZYX in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF12A→partner) and Y-score (partner→TNFRSF12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZYX →	+0.454	+1.414	<.001	<.001	3	7
COAD	PLAU →	+0.744	+1.221	.004	<.001	3	7
GBM	CCN1 →	+0.736	+0.858	<.001	<.001	3	7
BRCA	MET →	+0.719	+0.806	.001	.008	2	8
GBM	P3H1 →	+0.534	+0.845	<.001	<.001	3	6
GBM	P4HA2 →	+0.787	+0.754	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,128 associations by consensus.

TNFRSF12A vs ZYX — BRCA

Explore this scatter interactively →