TNFRSF12A

Across TCGA cell cohorts, TNFRSF12A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,156 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNFRSF12A-associated GO terms across cancer lineages are Regulation of protein maturation, Regulation of protein processing, and Integrin-mediated signaling pathway. Each is linked with TNFRSF12A in more than 16 cancer types. Because this analysis shows association rather than direction, both TNFRSF12A-to-partner and partner-to-TNFRSF12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein maturation grouped by TNFRSF12A-low versus TNFRSF12A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF12A→partner) and Y-score (partner→TNFRSF12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein maturation →	+0.195	+3.482	<.001	<.001	3	17
BONE	Regulation of protein processing →	+0.177	+3.482	<.001	<.001	3	17
BONE	Integrin-mediated signaling pathway →	+0.265	+4.172	<.001	<.001	3	15
BONE	Regulation of plasminogen activation →	+0.267	+3.281	<.001	<.001	3	15
BONE	Regulation of coagulation →	+0.195	+2.938	<.001	<.001	3	15
BONE	Positive regulation of chemotaxis →	+0.121	+2.874	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,156 associations by consensus.

Regulation of protein maturation by TNFRSF12A expression — BONE

Explore this box plot interactively →