TNFRSF11A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFRSF11A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,155 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFRSF11A-associated proteins across cancer lineages are TNFRSF11A_S580, PPP2R5E, and EHBP1L1. Each is linked with TNFRSF11A in more than 5 cancer types. Because this analysis shows association rather than direction, both TNFRSF11A-to-partner and partner-to-TNFRSF11A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF11A versus TNFRSF11A_S580 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF11A→partner) and Y-score (partner→TNFRSF11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTNFRSF11A_S580 →+0.637+0.453.003<.00136
GBMPPP2R5E →-0.312-0.738<.001.00135
GBMEHBP1L1 →+0.562+0.913<.001<.00135
BRCAPLA2G4A →+0.657+0.740<.001<.00135
BRCARALGAPA1 →-0.249-0.693.004<.00134
GBMRAP2B →+0.276+0.649<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,155 associations by consensus.

TNFRSF11A vs TNFRSF11A_S580 — OV

Per-sample scatter of TNFRSF11A vs TNFRSF11A_S580 in OV (Pearson r = 0.42).

Explore this scatter interactively →

Exploration