TNFRSF10D

Across TCGA pan-cancer cohorts, TNFRSF10D Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TNFRSF10D data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TNFRSF10D Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TNFRSF10D expression acts as an unfavorable survival marker.

COAD, SKCM, and CHOL are the cancer types where TNFRSF10D Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.001	0.871	<.001	14	view →
SKCM	DFS	Median	All	0.220	0.643	.005	12	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TNFRSF10D–COAD (OS)

Open the COAD breakdown →