TNFRSF10D

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFRSF10D protein abundance is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF10D-associated genes across cancer lineages are CRYM, CCDC114, and CSPG5. Each is linked with TNFRSF10D in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF10D-to-partner and partner-to-TNFRSF10D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF10D versus CRYM in UCEC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10D→partner) and Y-score (partner→TNFRSF10D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCRYM →-1.859-1.323<.001<.00131
UCECCCDC114 →-1.668-1.186.008.00531
UCECCSPG5 →-1.471-1.323<.001<.00131
UCECCFAP94 →-1.426-0.919.003.00131
UCECADGB →-1.941-1.186.002.00531
UCECDNAI1 →-2.016-1.186.009.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

TNFRSF10D vs CRYM — UCEC

Per-sample scatter of TNFRSF10D vs CRYM in UCEC (Pearson r = -0.58).

Explore this scatter interactively →

Exploration