TNFRSF10B

Across TCGA patient cohorts, TNFRSF10B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,514 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFRSF10B-associated proteins across cancer lineages are DOCK5, ARHGEF10, and CCDC25. Each is linked with TNFRSF10B in more than 7 cancer types. Because this analysis shows association rather than direction, both TNFRSF10B-to-partner and partner-to-TNFRSF10B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF10B versus DOCK5 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10B→partner) and Y-score (partner→TNFRSF10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DOCK5 →	+0.411	+0.761	<.001	<.001	3	8
BRCA	ARHGEF10 →	+0.336	+0.660	<.001	<.001	3	7
OV	CCDC25 →	+0.410	+0.663	<.001	<.001	3	7
OV	PPP2CB →	+0.600	+1.110	<.001	<.001	3	6
OV	XPO7 →	+0.256	+0.684	<.001	<.001	3	6
BRCA	ERI1 →	+0.508	+0.735	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,514 associations by consensus.

TNFRSF10B vs DOCK5 — BRCA

Explore this scatter interactively →