TNFRSF10B

Across TCGA cell cohorts, TNFRSF10B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,198 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNFRSF10B-associated GO terms across cancer lineages are Activation of NF-kappaB-inducing kinase activity, Cellular response to cell-matrix adhesion, and Negative regulation of translation in response to endoplasmic reticulum stress. Each is linked with TNFRSF10B in more than 13 cancer types. Because this analysis shows association rather than direction, both TNFRSF10B-to-partner and partner-to-TNFRSF10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Activation of NF-kappaB-inducing kinase activity grouped by TNFRSF10B-low versus TNFRSF10B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10B→partner) and Y-score (partner→TNFRSF10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Activation of NF-kappaB-inducing kinase activity →	+0.193	+1.504	<.001	<.001	3	14
BREAST	Cellular response to cell-matrix adhesion →	+0.508	+1.319	.008	.004	3	10
LARGE_INTESTINE	Negative regulation of translation in response to endoplasmic reticulum stress →	+0.144	+1.352	<.001	<.001	3	10
LUNG_SCLC	Myelination in peripheral nervous system →	+0.102	+2.409	.003	.003	2	11
LUNG_SCLC	Peripheral nervous system axon ensheathment →	+0.102	+2.409	.003	.003	2	11
PANCREAS	Regulation of protein processing →	+0.133	+0.863	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,198 associations by consensus.

Activation of NF-kappaB-inducing kinase activity by TNFRSF10B expression — LIVER

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