TNFRSF10A-AS1

Across TCGA pan-cancer cohorts, TNFRSF10A-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated TNFRSF10A-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TNFRSF10A-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TNFRSF10A-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

MESO, PAAD, and KIRC are the cancer types where TNFRSF10A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	II,III,IV	0.275	0.526	<.001	84	view →
PAAD	OS	Tertile	All	0.266	0.571	<.001	67	view →
KIRC	OS	Tertile	All	0.743	0.562	<.001	64	view →
LGG	OS	Median	All	0.859	0.930	<.001	48	view →
SKCM	OS	Median	All	0.403	0.280	.002	38	view →
STAD	DFS	Median	All	0.698	0.559	.006	30	view →
READ	OS	Quartile	II,III,IV	0.917	0.473	.001	26	view →
COAD	OS	Median	II,III,IV	0.915	0.797	.008	22	view →
LUSC	OS	Median	All	0.322	0.457	.008	17	view →
CHOL	DFS	Quartile	II,III,IV	0.754	0.135	.007	15	view →
LIHC	DFS	Tertile	All	0.483	0.640	.010	14	view →
PRAD	DFS	Tertile	All	0.970	0.903	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

TNFRSF10A-AS1–MESO (DFS)

Open the MESO breakdown →