Across TCGA patient cohorts, TNFAIP8L3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,262 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFAIP8L3-associated genes across cancer lineages are MEF2C, CXCL12, and MAN1C1. Each is linked with TNFAIP8L3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L3-to-partner and partner-to-TNFAIP8L3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L3→partner) and Y-score (partner→TNFAIP8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MEF2C →	+1.442	+0.774	<.001	<.001	3	7
HNSC	CXCL12 →	+1.511	+0.659	<.001	<.001	2	7
BRCA	MAN1C1 →	+0.649	+0.646	.001	.001	3	6
UCEC	RHOJ →	+0.966	+0.773	<.001	<.001	3	6
BRCA	FGD3 →	+0.954	+0.503	<.001	<.001	3	6
HNSC	ARHGEF6 →	+1.137	+0.815	.001	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,262 associations by consensus.

Exploration

TNFAIP8L3 survival (RNA) · tumor vs normal (RNA) · all TNFAIP8L3 data types