TNFAIP8L2

Across TCGA patient cohorts, TNFAIP8L2 mutation is significantly associated with the RNA expression of many other genes, with 354 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TNFAIP8L2-associated genes across cancer lineages are MTND5P35, MIR4714, and RN7SL778P. Each is linked with TNFAIP8L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L2-to-partner and partner-to-TNFAIP8L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND5P35 grouped by TNFAIP8L2-low versus TNFAIP8L2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L2→partner) and Y-score (partner→TNFAIP8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTND5P35 →	+0.031	+5.539	<.001	.004	3	2
BLCA	MIR4714 →	+0.693	+4.299	<.001	.007	3	2
UCEC	RN7SL778P →	+0.378	+2.815	.002	.008	3	2
CESC	HMGB4 →	+0.018	+5.306	<.001	.006	3	2
COAD	RNU6-522P →	+1.337	+5.392	<.001	.002	3	2
CESC	CCNJP1 →	+0.037	+5.669	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 354 associations by consensus.

MTND5P35 by TNFAIP8L2 expression — CESC

Explore this box plot interactively →