TNFAIP8L2

Across TCGA patient cohorts, TNFAIP8L2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFAIP8L2-associated genes across cancer lineages are CD8+ T-cells and Fibroblasts. Each is linked with TNFAIP8L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L2-to-partner and partner-to-TNFAIP8L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by TNFAIP8L2-low versus TNFAIP8L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L2→partner) and Y-score (partner→TNFAIP8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.017	+3.108	.021	.011	3	1
UCEC	Fibroblasts →	+0.035	+2.393	.010	.025	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by TNFAIP8L2 expression — UCEC

Explore this box plot interactively →