TNFAIP8L2

Across TCGA cell cohorts, TNFAIP8L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,443 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFAIP8L2-associated GO terms across cancer lineages are Cytosolic transport, Negative regulation of gene expression, epigenetic, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with TNFAIP8L2 in more than 10 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L2-to-partner and partner-to-TNFAIP8L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by TNFAIP8L2-low versus TNFAIP8L2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L2→partner) and Y-score (partner→TNFAIP8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cytosolic transport →	+0.045	+0.090	.002	.006	3	11
BONE	Negative regulation of gene expression, epigenetic →	+0.087	+0.125	<.001	<.001	3	9
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.168	+0.101	<.001	<.001	3	8
BONE	Viral transcription →	+0.124	+0.109	.001	.002	3	8
BONE	Epigenetic regulation of gene expression →	+0.071	+0.106	<.001	.004	3	8
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.081	+0.093	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,443 associations by consensus.

Cytosolic transport by TNFAIP8L2 expression — OVARY

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