TNFAIP6

Across TCGA pan-cancer cohorts, TNFAIP6 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TNFAIP6 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TNFAIP6 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TNFAIP6 expression acts as an unfavorable survival marker.

PDAC, LUAD, and LSCC are the cancer types where TNFAIP6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.279	0.534	<.001	42	view →
LUAD	OS	Median	III,IV	0.331	0.925	.007	25	view →
LSCC	DFS	Median	All	0.505	0.992	.003	15	view →
GBM	DFS	Quartile	All	0.620	0.939	.001	9	view →
HNSC	OS	Median	IV	0.641	0.910	.013	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TNFAIP6–PDAC (OS)

Open the PDAC breakdown →