TNFAIP6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TNFAIP6 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TNFAIP6-associated genes across cancer lineages are OR7D4 and OR10G2. Each is linked with TNFAIP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFAIP6-to-partner and partner-to-TNFAIP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7D4 grouped by TNFAIP6-low versus TNFAIP6-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP6→partner) and Y-score (partner→TNFAIP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYOR7D4 →+0.056+5.196<.001.00531
OVARYOR10G2 →+0.026+5.196<.001.00531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR7D4 by TNFAIP6 expression — OVARY

Box plot of OR7D4 in TNFAIP6-low vs TNFAIP6-high samples in OVARY.

Explore this box plot interactively →

Exploration