TNFAIP1

Across TCGA cell cohorts, TNFAIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,641 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFAIP1-associated GO terms across cancer lineages are Establishment or maintenance of cell polarity, Vesicle-mediated transport to the plasma membrane, and Endosomal transport. Each is linked with TNFAIP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TNFAIP1-to-partner and partner-to-TNFAIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of cell polarity grouped by TNFAIP1-low versus TNFAIP1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP1→partner) and Y-score (partner→TNFAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Establishment or maintenance of cell polarity →	+0.056	+0.692	.003	.003	3	12
BONE	Vesicle-mediated transport to the plasma membrane →	+0.097	+0.977	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.059	+0.829	.003	<.001	3	12
BONE	Regulation of protein K48-linked ubiquitination →	+0.148	+0.785	.004	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.058	+0.780	.008	.007	3	12
BONE	Wound healing →	+0.127	+0.804	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,641 associations by consensus.

Establishment or maintenance of cell polarity by TNFAIP1 expression — KIDNEY

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