TNFAIP1

Across TCGA cell cohorts, TNFAIP1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFAIP1-associated genes across cancer lineages are AWAT2, ELSPBP1, and OR56A1. Each is linked with TNFAIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFAIP1-to-partner and partner-to-TNFAIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AWAT2 grouped by TNFAIP1-low versus TNFAIP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP1→partner) and Y-score (partner→TNFAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AWAT2 →	+0.010	+4.705	.004	.003	3	1
BLOOD_Leukemia	ELSPBP1 →	+0.050	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR56A1 →	+0.071	+4.276	<.001	.007	3	1
BLOOD_Leukemia	TCP11X2 →	+0.151	+5.060	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

AWAT2 by TNFAIP1 expression — BLOOD_Leukemia

Explore this box plot interactively →