TMUB1

Across TCGA cell cohorts, TMUB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,932 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMUB1-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Pre-mRNA catabolic process, and Regulation of autophagosome maturation. Each is linked with TMUB1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMUB1-to-partner and partner-to-TMUB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by TMUB1-low versus TMUB1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMUB1→partner) and Y-score (partner→TMUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.198	+1.275	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.203	+0.955	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of autophagosome maturation →	+0.075	+0.785	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of synaptic vesicle exocytosis →	+0.153	+0.775	.002	.001	3	9
PANCREAS	Regulation of isotype switching to IgG isotypes →	+0.102	+0.590	<.001	.003	3	9
BONE	Viral translational termination-reinitiation →	+0.075	+1.116	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,932 associations by consensus.

Transcription pausing by RNA polymerase II by TMUB1 expression — BONE

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